IPeptide yesikoUkudibanisaInkonzo
IHangzhou Yiya phezulu kwiPeptide Biotech , esekwe ngo-2014, i IShishini leSizwe lobuchwephesha obuphezuluigxile kuphando, uphuhliso kunye nokuveliswa kweepeptides kunye nezinto ezinxulumene nazo.
Yenkampaniiziko lophando peptideokwangoku ibekwe kwiSithili saseQiantangof IHangzhou, egubungela indawo engaphezulu kwe-3,000 yeemitha zesikwere.Iinkampani's umzi-mveliso itholakala kwi-No.24, i-Haitian Road, iSithili saseShangyu, isixeko saseShaoxing, kwiphondo laseZhejiang.Kukho kwakhona izityalo ezimbini zentsebenziswano, enye yeyeimveliso ye-peptide ye-GMP ibekwe kwiAnji kwisiphaluka kwiphondo Zhejiang, enye yeyemolekyuli encinci ye-API ebekwe kuyoIsixeko saseYuncheng kwiphondo laseShanxi.Sibaishishini lobuchwepheshe obuphezulu, ukudibanisa uphando, ukulinganisa ukulinganisa, ukuthengisa kunye nokuthengiswa kwehlabathi.
Inkampani iyengaphaya100abasebenzi,kwaye uyeiphuhliswe ngaphezu40 amayeza akhulileyoiipeptides,engaphezulu kweI-10 lamalungelo awodwa omenzi wechizazigunyazisiwe.Tyena ngonyaka umthamo wemvelisois ixhomekeke kuIikhilogram ezili-100, inani leepeptides eziqhelekileyo bafikelele kuma-20,000.Singabonelela ngeenkonzo zokuma kwepeptide ukusuka kuphando (mg) ukuya kurhwebo (KGs).
Uluhlu loLungiso lwePeptide
N-ukulungiswa kwetheminali
| {N-Me-Ala} | {N-Me-Asp} | {N-Me-Glu} | {N-Me-Ile} |
| {N-Me-Leu} | {N-Me-Met} | {N-Me-Nle} | {N-Me-Nva} |
| {N-Me-Phe} | {N-Me-Ser} | {N-Me-Thr} | {N-Me-Tyr} |
| {N-Me-Val} | {Sar} | N-Me-Arg | N-Me-Asn |
| N-Me-beta-Ala | N-Me-Gln | N-Me-Lys | N-Me-Trp |
C-ukulungiswa kwetheminali
| {Ibhulorho yeMono Disulfide} | {Ibhulorho ephindwe kabini yeDisulfide} | {Ibhulorho ye-Triple Disulfide} |
| {Ibhulorho ye-Disulfide engaqhelekanga} | {ISeq efanayo.Ibhulorho ye-Inter-Disulfide } | {Ibhulorho eDifferent Inter-Disulfide} |
| {Amide ibhayisekile (ekupheleni)} | {Amide cyclic (Itsheyini esecaleni)} | {Orn side chain Amide cyclic} |
| {Thioester cyclic} | {lactone cyclic} | {Sec cyclic} |
Ii-amino acids ezingaqhelekanga
| {2-Aze} | {3-Aze} | {5,5-Dime-Pro} |
| {5-ASA} | {Abu} | {Ac-Ls} |
| {Ayib} | {Beta-Asp} | {Bpa} |
| {Cha} | {Chg} | {Cit} |
| {Cpg} | {Cys(Acm)} | {Cys(Bzl)} |
I-Isotope ebhalwe iipeptides
| Lys(13C6,15N2) | I-Ile(13C6,15N) |
| I-Leu(13C6,15N) | IVal(13C5, 15N) |
| Arg(13C6, 15N4) |
Fluorescent peptide modifications/FRET pairs
| Biotin- | Dansyl- | Ipeptide enefluorecent ecinyiweyo |
| I-Biotin-Ahx- | Dansyl-Ahx- | Dabcyl |
| 5-FAM- | Cy3- | Dabcyl / Glu (Edans)-NH2 |
| 5-FAM-Ahx- | Cy5- | Dansyl- |
| FITC- | I-MCA/DNP | Dansyl-Ahx- |
| FITC-Ahx- | AMC | Edans / Dabcyl |
Peptide Conjugates
| BSA(-COOH ye-C terminal | I-KLH(-NH2 ye-N terminal) | I-OVA(-COOH ye-C terminal) |
| Ukudibanisa kwe-BSA kwi-Cys | Ukudibanisa kwe-KLH kwi-Cys | I-OVA(-NH2 ye-N terminal) |
| Ukudibanisa kwe-OVA kwiCys |
Phosphorylation
| {pSer} | {D-pSer} |
| {pTyr} | {D-pTyr} |
| {pThr} | {D-pThr} |
Olunye uhlengahlengiso(PEGylation, Cyclic modifications, Disulfide Bridges)
| I-PEGylation | Ukuguqulwa kwebhayisekile | Iibhulorho zeDisulfide |
| {Mini-PEG1} | Intloko ukuya emsileni cyclic | {Ibhulorho yeMono Disulfide} |
| {Mini-PEG2} | {Ibhulorho ephindwe kabini yeDisulfide} | |
| {PEG-11} | {Ibhulorho ye-Triple Disulfide} | |
| {PEG-12} | {Ibhulorho ye-Disulfide engaqhelekanga} | |
| …… | …… | …… |