Terlipressin acetate

Inombolo yeMveliso: GT-D009

Igama lesiNgesi: Terlipressin acetate

Igama lesiNgesi: Terlipressin acetate

Ulandelelwano: I-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Ibhulorho ye-Disulfide: Cys4-Cys9)

CAS: 1884420-36-3

Ubunyulu: ≥98% (HPLC)

Ifomula yemolekyuli: C52H74N16O15S2

Ubunzima bemolekyuli: 1227.37

Ukubonakala: umgubo omhlophe

Iimeko zokugcina: Gcina kwi -20 ° C, ukushisa okuphantsi kwaye ukhuselwe ekukhanyeni

Ukunyibilika: H2O: 100 mg/mL (74.21 mM; Ifuna i-ultrasonic) DMSO: 100 mg/mL (74.21 mM; Kufuneka i-ultrasonic)

Terlipressin acetate

Ngathi:

I-Terlipressin, ikhemikhali eyaziwa ngokuba yi-triglycyl-lysine vasopressin, yindlela entsha yokwenziwa kwe-vasopressin esebenza ixesha elide.Yiprodrug engasebenziyo kwaye ngokukhawuleza "ikhutshwa" kwi-lysine vasopressin esebenzayo kwi-vivo ngesenzo se-aminopeptidase ukususa iintsalela ze-glycylyl kwi-N terminus yayo.Ke ngoko, i-terlipressin ilingana ne-reservoir ye-lysine vasopressin ekhutshwa ngesantya esizinzileyo.