I-tripeptide yetyhefu yenyoka

Umzobo wesakhiwo se-serpentin-like venom triplet peptide:

I-tripeptide yetyhefu yenyoka

Imigangatho yohlalutyo,HPLC≥98%

I-tripeptide yetyhefu yenyoka

(2S) -beta-alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)butanamide acetate

Isibizo: (2S) -beta-alanyl-L-prolyl-2, 4-diamino-N -(benzyl) butyamido acetate;(2S) -beta-alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)butanamide acetate;I-SYN-AKE;inyoka-tripeptide;H – beta – Ala – Pro – Dab – NHBzl.2 acoh;Inyoka tr

Inombolo ye-CAS: 823202-99-9

Ifomula yemolekyuli: C19H29N5O3.2(C2H4O2)

Ubunzima bemolekyuli: 495.58

Intshayelelo:

Ulandelelwano: H-β-Ala-Pro-Dab-NH-Bzl

Ukubonakala: umgubo omhlophe

Ngathi:

Ityhefu efana nepeptide yipeptide encinci elinganisa umsebenzi wetyhefu yenyoka, kwaye endaweni yetyhefu yenyoka, yipeptide esebenzayo efana nesakhiwo setyhefu yenyoka.I-peptide yetyhefu yayisebenza ngokuphindwe kahlanu kune-botulinum ekunciphiseni imibimbi, kwaye yafunyanwa ukunciphisa imibimbi ngama-52 ekhulwini emva kweentsuku ezingama-28 zokusetyenziswa ebantwini.

Izibonelelo:

1. Ukuchasa imibimbi kunye nokuchasa ukuguga

2. Ukuphucula umgangatho wolusu

3. Ubuso, intamo kunye neemveliso zokunakekelwa kwezandla

4. Ukuphucula ukuthungwa kwesikhumba, yenza ulusu lube lula kwaye luthambile, luphucule umbala

5. Inokungena kuluhlu olunzulu lwesikhumba, izalise icollagen, kwaye isuse imikhondo eshiywe yiminyaka.

6. Dlala indima ye-moisturizing kunye ne-hydrating, yenza ulusu lube lukhuni kwaye lubushelelezi, lukhanyise kwaye luhle

7. Qinisa ukunqanda imibimbi, phinda uqinise ubuso obume okwe-V, kwaye ubuyisele ulusu lobutsha.

8. Ukuthintela ukuveliswa kwe-melanin yesikhumba

Indima:

I-dipeptide diamino-butadibenzyl amide diacetate/venom efana ne-tripeptide iyimveliso esebenzayo egudileyo kunye ne-anti-crease esebenzayo ngokuphumla kwemisipha yobuso ngendlela ehambelana ne-Waglerin 1, i-neuromuscular blocking compound ye-Temple Viper venom.I-tripeptides yesihlungu senyoka isebenza kwiimbrane ze-postsynaptic kwaye zichasene nokuguqulwa kwe-muscle nicotinic acetylcholine receptor (nmAChR).I-tripeptide yesihlungu senyoka ibophelela kwi-ε subunit ye-nmAChR kwaye ivimba ukubophelela kwe-acetylcholine kwi-receptor, okubangela ukuvalwa kwe-receptor.Kwimeko evaliweyo, i-sodium ion ayinakungeniswa kwaye i-depolarized, kwaye ukuhanjiswa kwe-nerve excitation kuvaliwe, ngoko ke ukuphumla kwemisipha.