Palmitoyl Tripeptide-8/936544-53-5/GT Peptide/Peptide Supplier

Inkcazo

I-Pal-Lysyl-Valyl-Lysine (i-Pal-Lys-Val-Lys-OH), ekwaziwa ngokuba yi "tripeptide" okanye "collagen peptide Col-O2", yeyona peptide yokuqala kwaye isetyenziswa kakhulu.I-Palmitoyl tripeptide-8 yi-peptide yomqondiso ekhuthaza ukuhlanganiswa kwe-Chemicalbook kunye ne-extracellular matrix protein protein ye-collagen (iintloboⅠ, ⅡkwayeⅣ) ngokunyuka komsebenzi we-stromal cell, okwenza ulusu lubukeke luncinci kwaye lukwazi ukuqina.Xa ifakwe kwizinto zokuthambisa, inokunceda ukubuyisela i-collagen eluswini, ukuphucula ukunyameka kobuso kunye nokunciphisa kakhulu imibimbi yobuso.Ngelo xesha, nayo ineempawu zokuphucula umsebenzi weeseli, ukwandisa umthamo wamanzi wesikhumba, ukuphucula ukukhanya kwesikhumba kunye nokuphucula ithoni yesikhumba.Ukuphucula ukufuma kwesikhumba kunye nokugcinwa kokufuma, yenza ulusu luzive luthambile kwaye lugudileyo, ukusuka ngaphakathi ukuqaqambisa ulusu alusekho buthuntu.

Iinkcukacha

Imbonakalo: Imhlophe ukuya kumgubo omhlophe

Ubunyulu(HPLC):≥98.0%

Ukungacoceki okukodwa:≤2.0%

Umxholo we-Acetate(HPLC): 5.0%～12.0%

Isiqulatho samanzi (uKarl Fischer):≤10.0%

Umxholo wePeptide:≥80.0%

Ukupakisha kunye nokuThumela: Ukushisa okuphantsi, ukupakisha i-vacuum, ngokuchanekileyo kwi-mg njengoko kufuneka.

Ungaodola Njani?

1. Contact us directly by phone or email: +86-13735575465, sales1@gotopbio.com.

2. Oda kwi-intanethi.Nceda ugcwalise ifom ye-odolo ye-intanethi.

3. Nika igama le-peptide, inombolo ye-CAS okanye ulandelelwano, ukucoceka kunye nokuguqulwa ukuba kuyimfuneko, ubungakanani, njl.njl. siya kubonelela ngekowuteshini kwiiyure ezi-2.

4. Umyalelo wokuthotyelwa kwemvumelwano yokuthengisa esayiniweyo ngokufanelekileyo kunye ne-NDA (isivumelwano esingaveziyo) okanye isivumelwano esiyimfihlo.

5. Siya kuqhubeka sihlaziya inkqubo ye-odolo ngexesha.

6. Ukuhanjiswa kwePeptide yi-DHL, Fedex okanye abanye, kunye ne-HPLC, MS, COA iya kubonelelwa kunye nomthwalo.

7. Umgaqo-nkqubo wembuyekezo uya kulandelwa ukuba kukho ukungangqinelani komgangatho okanye inkonzo yethu.

8. Inkonzo emva kokuthengisa: Ukuba abathengi bethu banemibuzo malunga nepeptide yethu ngexesha lovavanyo, nceda uzive ukhululekile ukuqhagamshelana nathi kwaye siya kuyiphendula ngexesha elifutshane.

Zonke iimveliso zenkampani zisetyenziselwa kuphela injongo yophando lwesayensi, yona'Ithintelwe ukuba isetyenziswe ngokuthe ngqo nguye nawuphi na umntu emzimbeni womntu.

FAQ

Yeyiphi imida kubude beepeptides zokwenziwa?

I-polypeptide eyenziwe yinkampani yethu yi-6 ~ 50 amino acids ubude.Iinkqubo eziqhelekileyo zesigaba esiqinileyo se-synthesis ngokuqhelekileyo zivelisa i-peptides ye-6 ukuya kwi-50 ye-amino acids.

Uzichaza njani iincopho ze-P+Na kunye ne-P+K kwi-MALDI(MS)?

Incochoyi ye-Na kunye ne-K idla ngokubonwa kwi-MALDI, kwaye i-sodium kunye ne-potassium ziphuma emanzini anyibilikayo.Kwanamanzi adityanisiweyo kunye namanzi adibeneyo anokuqulatha izixa zesodium kunye ne-potassium ion ezingenakususwa ngokupheleleyo.Zikwayiyoni kwaye zibophelela kwiqela le-carboxyl yasimahla yepeptide ngexesha le-mass spectrometry.Ngenxa yokuba akukho nkqubo yokucoca yokususa i-sodium kunye ne-potassium ion emanzini, ngamanye amaxesha akunakuphepheka ukuba iincopho zesodium kunye ne-potassium zivela kwimephu ye-MALDI MS.

Nceda uchaze isicwangciso sakho sokucoca

Iipeptides ezidityaniswe yinkampani yethu zacocwa ngokulungiswa kwesigaba se-HPLC esilungisiweyo kunye ne-TFA kunye ne-pH 2 yongezwe kuzo zombini izigaba zeselula.Isigaba A yi-0.1% ye-TFA kumanzi a-ultra-pure, kwaye isigaba B yi-0.1% ye-TFA kwi-ACN, i-pH 2. Isampuli inokuchithwa ngokuthe ngqo kwi-A isigaba, okanye ichithwe kwisixa esincinci se-B kwaye ihlanjululwe ngesigaba se-A.Ngamanye amaxesha kunokuba yimfuneko ukunyibilikisa i-hydrophobic peptides ene-solvents ezinamandla ezifana ne-formic acid okanye i-acetic acid, kuxhomekeke kulandelelwano lwe-peptide.Kwi-pH 6.8, ngokuqhelekileyo kunzima ukunyibilikisa kunye nokucoca i-peptide, ngoko ke siqhele ukunyibilikisa i-peptide kuqala kwaye emva koko sisebenzise izigaba ezibini eziphathwayo zokukhanya kwegradient.Isisombululo se-buffer kwi-pH 6.8 yayiyi-10 mM i-acetate ye-ammonium kumanzi ahlambulukileyo (i-mobile phase A), i-ACN ecocekileyo (isigaba se-mobile B).Amacandelo ahlukeneyo aqokelelwa aza achongwa yi-MADLI-TOF MS.Ubunyulu buhlalutywe yi-HPLC yesigaba esibuyiselwe umva.Emva koko, i-peptides ekujoliswe kuyo yayiyi-lyophilized, kwaye i-lyophilized peptides yadityaniswa kwiibhotile ezincinci.

Uzibeka njani esweni iimveliso zakho?

Zonke iipeptide zokwenziwa zahlalutywa yi-HPLC kunye ne-MS, ngaphandle kwe-MALDIMS.Kuba iipeptide zenziwe nge-ionized ngokulandelelana kwazo kwiispectrometers zobunzima ezahlukeneyo, ubuchule be-HPLC-MS bunokusetyenziswa ukuhlalutya ezo zincopho ze-ionization kwi-HPLC.Izixhobo zethu zobugcisa [MALDI-MS, HPLC-(ESI)MS (i-ion trap kunye ne-tetrode array)] ibonelela ngesiqinisekiso esithembekileyo sokuhlalutya.

Ngaba ukunyibilika kwepeptide kunxulumene nomgangatho wepeptide?

Iipeptides zokwenziwa azinyibiliki kakuhle, iipeptides zinengxaki, akunjalo?

A: Kunzima ukuqikelela ukuba injani na i-peptide enyibilikayo kunye nokuba yintoni na isinyibilikisi esifanelekileyo.Akuyonyani ukuba kukho ingxaki nge-peptide synthesis ukuba kunzima ukuyinyibilika.

Uzigcina njani iipeptides kwisisombululo?

Ukuba kufuneka ugcine iipeptides zakho kulwelo, sebenzisa isithinteli esintsholongwane e-PH 5-6 kwaye ugcine ku -20℃ukwandisa ubomi beepeptide zakho kwisisombululo.

Ingaba iipeptides zihlala ixesha elingakanani kwisinyibiliko?

Kungcono ukuba ungagcini iipeptide eziseleyo kwisisombululo.Ubomi beshelufu ye-polypeptides kwisisombululo buncinci kakhulu, ngakumbi abo bane-cysteine, i-methionine, i-tryptophan, i-asparagic acid, i-glutamic acid, kunye ne-N-terminal glutamic acid ngokulandelelana.Ngokubanzi, thabatha inani elifunekayo lokusetyenziswa, intsalela yomkhenkce yomiswe ukugcinwa kwexesha elide.